Table 1

PCOS SNPs used to construct the main instrument variable in Europeans

Chr:positionSNPEffect alleleOther alleleEAFβSENearest genePF statistic
2:43561780rs7563201AG0.451−0.1080.017THADA3.68E−1039.50
2:213391766rs2178575AG0.1510.1660.022ERBB43.34E−1457.66
5:131813204rs13164856TC0.7290.1240.019IRF1/RAD501.45E−1040.95
8:11623889rs804279AT0.2620.1280.018GATA4/NEIL23.76E−1248.09
9:5440589rs10739076AC0.3080.1100.020PLGRKT2.51E−0831.01
9:97723266rs7864171AG0.428−0.0930.017C9orf32.95E−0830.84
9:126619233rs9696009AG0.0680.2020.031DENND1A7.96E−1142.19
11:30226356rs11031005TC0.854−0.1590.022ARL14EP/FSHB8.66E−1351.03
11:102043240rs11225154AG0.0940.1790.027YAP15.44E−1143.16
11:113949232rs1784692TC0.8240.1440.023ZBTB161.88E−1040.49
12:56477694rs2271194AT0.4160.0970.017ERBB3/RAB5B4.57E−0934.22
12:75941042rs1795379TC0.240−0.1170.020KRR11.81E−0936.25
16:52375777rs8043701AT0.815−0.1270.021TOX39.61E−1037.46
2:49247832rs2349415TC0.3430.0760.017FSHR9.59E−0619.65
  • Chr, chromosome; EAF, effect allele frequency.