Table 1

Overview of the [68Ga]S02-GIP-T4 PET/CT dose escalation and drug target occupancy studies in NHPs

Scan 1Scan 2Scan 3
Study typeNHP identifierWeight (kg)μg/kgMBq/kgμg/kgMBq/kgμg/kgMBq/kg
Dose escalation16.30.0280.259.76.2NANA
24.00.0340.353.011.3NANA
35.60.0310.358.87.9NANA
44.30.0810.80.491.22.51.5
54.30.151.41.11.77.62.9
Scan 1InterventionScan 2
NHP identifierWeight (kg)μg/kgMBq/kgμg/kg TA12μg/kgMBq/kg
Occupancy24.20.0460.5500.0220.3
35.30.0330.4500.0210.3
64.10.0410.4500.030.4
  • NA, not applicable.