Table 2

Indices of whole-body glucose homeostasis under CE and TN conditions

ParametersBAT (n = 5)BAT+ (n = 7)
TNCETNCE
Basal conditions
 Glucose (mg/mL)90.0 ± 7.994.0 ± 3.493.4 ± 2.089.5 ± 3.2
 Whole-body glucose disposal (μmol/kg/min)9.4 ± 0.79.7 ± 0.610.2 ± 0.511.6 ± 0.2*
 Insulin (μU/mL)8.6 ± 4.08.2 ± 1.33.9 ± 0.83.8 ± 1.0
Hyperinsulinemic-euglycemic conditions
 Glucose (mg/mL)83.8 ± 3.185.8 ± 3.581.1 ± 3.381.5 ± 5.8
 Whole-body glucose disposal (μmol/kg/min)12.4 ± 2.2‡12.8 ± 1.813.0 ± 0.916.5 ± 1.1*,
 Endogenous glucose production (μmol/kg/min)5.6 ± 1.67.5 ± 1.15.3 ± 1.76.3 ± 1.3
 Suppression of endogenous glucose production (%)−59.7 ± 9.4−48.2 ± 6.9−62.4 ± 12.5−59.1 ± 9.1
 Insulin (μU/mL)33.5 ± 4.331.0 ± 6.718.2 ± 2.018.8 ± 2.0
  • Data are mean ± SEM.

  • *P < 0.05, CE vs. TN conditions.

  • P < 0.05, BAT vs. BAT+ subjects.

  • P < 0.05, basal vs. hyperinsulinemic-euglycemic conditions.